Injections for Smile Lines (Nasolabial Folds) in Tel Aviv and Petah Tikva

Nasolabial Folds filling young lady

Nasolabial folds are the deep lines that give the face a tired and aged appearance. Did you know they can be naturally and quickly filled without surgery? The leading and proven solution is hyaluronic acid injections for smile lines (nasolabial folds).

What Are Nasolabial Folds and What Causes Them?
Nasolabial folds are the skin creases that run from the sides of the nose down toward the corners of the mouth. They are called “smile lines” because they become more prominent when we smile. These lines often begin to appear in many people in their early 30s. Their formation is due to the loss of collagen and elastin, as well as the sinking of the fat tissues in the cheeks caused by gravity and volume loss. The combination of cheek volume loss and the natural decline in skin hydration leads to deeper nasolabial folds.

Hyaluronic Acid Injections for Smile Lines: How It Works
The leading solution for filling and softening nasolabial folds is hyaluronic acid. This gel-like substance occurs naturally in the body and primarily functions to maintain skin hydration and volume. When hyaluronic acid is injected directly into a nasolabial fold, it fills the line from within, adds volume, and immediately softens the crease. It is an extremely safe material, as it is not foreign to the body. Using hyaluronic acid injections for nasolabial folds allows us to restore lost volume and give the face a younger, fresher, and more natural appearance.

Hyaluronic Acid Injection Procedure – 4 Main Steps

  1. Consultation, Assessment, and Marking: The process begins with a professional consultation. Our doctor evaluates the depth of the folds, facial structure, and determines the required amount of filler. We often recommend combining this treatment with cheek enhancement to naturally lift and volumize the cheeks, which also softens the fold. The doctor marks the precise injection points on the skin.

  2. Cleansing and Local Anesthesia: The treatment area is thoroughly disinfected. Most modern fillers already contain lidocaine (a local anesthetic), making the injection minimally uncomfortable.

  3. Injections: The doctor performs slow, precise injections of hyaluronic acid into the fold. The injection process usually takes 5–10 minutes.

  4. Massage and Shaping: After the injections, the doctor gently massages and shapes the area to ensure even distribution and achieve the most natural, optimal result.

What to Expect After Hyaluronic Acid Injections for Nasolabial Folds
One of the major advantages of hyaluronic acid filler for nasolabial folds is the immediate effect. Once injected, the fold appears fuller and smoother. Mild swelling and redness may occur, slightly affecting the final appearance. The full effect is usually visible within 24–48 hours, once initial swelling subsides.

Hyaluronic acid is long-lasting, with results expected to last an average of 12–18 months. The duration may vary depending on the patient and the specific type of filler used.

Treatment Comparison: Hyaluronic Acid vs. Alternatives for Nasolabial Folds

Parameter Hyaluronic Acid for Smile Lines Facial Botox Medical Peel Facelift Surgery
Mechanism Fills fold and restores volume Paralyzes muscles beneath fold Exfoliates and renews skin Surgical skin tightening
Duration 8–18 months 3–6 months 6 months 5–10 years
Time to Effect Immediate 3–14 days 2 weeks 3–6 months
Price 1,200–1,700₪ 600–1,000₪ (per area) 1,000–1,300₪ 20,000–40,000₪
Pain Minimal Minimal Moderate High
Reversible Yes (with hyaluronidase) No No No

As shown, hyaluronic acid filler offers an optimal combination of immediate results, relatively long-lasting effect, and reversibility. While Botox is better suited for dynamic expression lines (forehead, glabella), hyaluronic acid injections for smile lines are the primary choice for deep, static folds like nasolabial lines.

Side Effects of Hyaluronic Acid Injections for Smile Lines
Hyaluronic acid injections for nasolabial folds are generally safe with a very low risk profile. Most patients report only mild side effects, if any.

Common effects include slight swelling or redness at the injection points, usually resolving within 1–2 days. Rarely, small bruises may appear, disappearing within a few days.

In very rare cases, minor asymmetry or small lumps may occur, correctable with a brief touch-up or additional enzymatic treatment. Avoiding blood thinners (like aspirin) before treatment, when medically possible, can reduce bruising risk. Consult with us if this applies.

Who Is Suitable for Hyaluronic Acid Injections for Nasolabial Folds?

Suitable Candidates:

  • Individuals aged 30+ whose smile lines are deepening.

  • Those with moderate to deep nasolabial folds.

  • Anyone seeking immediate results without significant downtime.

Not Recommended or Requires Caution:

  • Pregnant or breastfeeding women.

  • Patients with active infection, herpes, or inflammation at the treatment site.

  • Individuals with known allergies to fillers or lidocaine.

  • Patients with severe clotting disorders or active autoimmune diseases.

During the initial consultation, a thorough medical evaluation ensures suitability for treatment.

Cost and Considerations
Hyaluronic acid filler for nasolabial folds typically costs 1,200–1,700₪ per syringe, depending on the quantity and type of filler used. Considering its 12–18 month duration, this treatment is often more cost-effective long-term than frequent Botox sessions. It can also be combined with lip filler or jawline sculpting for a harmonious look.

Complementary Treatments for a Complete Facial Rejuvenation
Often, an aged or tired appearance involves more than nasolabial folds. For optimal results, we recommend combining hyaluronic acid injections for nasolabial folds with other aesthetic procedures, such as:

  • Lip filler

  • Cheek enhancement

  • PRP (vampire facial) to stimulate collagen and improve skin texture

  • Medical peels for skin renewal

  • Botox for other expression lines

These combinations create a balanced, harmonious facial appearance.

Rediscover Your Natural Smile
Smile lines are a natural part of aging, but you don’t have to live with them. Hyaluronic acid injections are safe, effective, and fast, restoring lost volume and softening folds. At PRP Clinic, our experienced team is committed to providing professional care and natural-looking results.

Schedule a personal consultation to start your journey toward smoother, younger-looking skin.

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About PRP Clinic

PRP clinic is a clinic specializing in aesthetic treatments and PRP, iPRF, PRGF, CGF and mesotherapy injections in Tel Aviv and Haifa:

Regenerative treatments
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  • Regenera
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  • Nose sculpting – everything you wanted to know
  • Lip thickening – filling with hyaluronic acid
  • Filling eye sockets
  • Shaping cheekbones and filling cheeks with hyaluronic acid
  • Sculpting and shaping the jaw line
  • The wonders of Botox for the face – refreshing the appearance easily
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  • Buttock shaping and sculpting with hyaluronic acid – buttock augmentation
  • Penis enlargement – thickening of the penis without surgery using hyaluronic acid
  • PRP injection into the penis, a natural treatment to strengthen erection, impotence and premature ejaculation
  • Botox injection into the penis
  • Breast augmentation without surgery
  • Eliminating / blurring stretch marks using PRP (vampire) treatment
  • Plasma gel / natural filler – a 100% natural filler that has an effect similar to acid
  • Rejuvenation and firming of the neck – treatment of neck wrinkles
  • Eliminating / filling smoking lines above the upper lip – barcode lines
  • Everything you wanted to know about mesotherapy
  • Skin Booster – the complete guide
  • Rejuvenation of palms (Profilo)
  • PRP treatment for the face – vampire treatment
  • PRP injection to the knee
  • PRP to the shoulder – can an injection of plasma to the shoulder prevent surgery?